TNFSF9 and neoplasm: The importance of the knowledge about the concurrent expression of immune stimulatory and immune suppressive ICMs on individual tumor tissue should be shown with the following example: CD137-L was significantly increased on MDA-MB-231 cells after normo-fractionated RT in combination with MH at 39 °C or 41 °C on day 3 after treatment, while for MCF-7 cells, MH heating at 44 °C was required.