To establish the effect of BDNF Val66Met polymorphism in heart remodeling after MI, the BDNFVal/Val and homozygous BDNFMet/Met mice underwent left anterior descending (LAD) coronary artery ligation, and cardiac morphology and function were assessed by cMRI at 24 h and 1, 4, and 8 weeks after surgery. The gene discussed is BDNF; the disease is myocardial infarction.