IL6 and Autoimmunity: In a murine model of type 1 diabetes, dietary treatment with ω-3 PUFAs reduced the incidence of autoimmunity in pancreatic islets, modulated the differentiation of Th- and T-regulatory cells, and decreased the levels of pro-inflammatory mediators such as IFN-γ, IL-17, IL-6, and TNF-α [123].