MEN1 and adrenal gland neoplasm: Adrenal tumours were detected from 12 to 15 months of age in male and female 129S6/SvEv Men1+/- mice, respectively, but from 19 and 18 months of age in male and female C57BL/6 Men1+/- mice, respectively, thereby indicating a significant earlier age for development of adrenal tumours in the 129S6/SvEv Men1+/- mice than the C57BL/6 Men1+/- mice (P < 0.0005, Fig. 1).