Fig 3 depicts weekly TAUS images of EOC tumor implant over time in ID8-luc without ascites (A) and in ID8-VEGF (B). To test whether TAUS can be used to detect PDX tumor, we injected mice (n = 5) with a PDX single cell suspension of EOC human cells. We were able to detect tumor growth for a human PDX tumor of high grade serous EOC at 10 days post injection (1.893mm in long axis). Longitudinal imaging demonstrated increased growth on days 14 (2.200mm in long axis) and 21 (3.875mm in long axis), respectively. (S2 Fig). This evidence concerns the gene VEGFA and neoplasm.