Also, decreased expression of GABRA2 in Scn1a ± mice served as a model of Dravet syndrome (Follwaczny et al., 2017; Hawkins, Zachwieja, Miller, Anderson, & Kearney, 2016), and increased expression observed in Pumilio‐2–deficient mice resulted in enhanced seizure susceptibility and the manifestation of epilepsy in the hippocampus (Follwaczny et al., 2017). The gene discussed is GABRA2; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.