Because sleep is important for normal brain function and is disrupted in various neuropsychiatric disorders (Hobson & Pace‐Schott, 2002), and PTPRD has been implicated in restless leg syndrome (Schormair et al, 2008), we further explored this phenotype by performing 24‐h EEG (electroencephalogram) and EMG (electromyogram) recordings to determine whether mice are in WAKE, NREM (non‐rapid eye movement sleep), or REM (rapid eye movement sleep) states (Fig 6A). This evidence concerns the gene PTPRD and restless legs syndrome.