The results of One-way ANOVA test showed a significantdifference in PGC-1α variables (F=72.33, df=7, P=0.001).Also, results of Turkey’s test showed that the mean serumlevels of PGC-1α in the diabetic+endurance traininggroup, endurance training group and diabetes+endurancetraining+DCA was significantly lower than the controlgroup (P≤0.01). Here, PPARGC1A is linked to diabetes mellitus.