SOAT1 and leukemia: For example, corticosteroid resistance in human leukaemia can be associated with enhanced Toll‐like receptor stimulation, resulting in enhanced JAK‐STAT and PI3K signalling and epigenetic de‐repression of expression of the anti‐apoptotic molecule BIM, all of which could theoretically confer cross‐resistance to a variety of antineoplastic agents.28