,61 Furthermore, as cytokines can assist tumor progression, targeting IL-4, IL-13, IL-10, TGF-β, and CXCL5 or enhancing IFN-γ and some chemokines (e.g., CCL2, CCL3, CXCL9, CXCL10) may inhibit tumor invasion and metastasis. This evidence concerns the gene IFNG and neoplasm.