Researchers have concluded that in atherosclerosis, interleukins such as IL-4, IL-13, and IL-10 activate specific transcription factors (e.g., STAT3 and STAT6, IFN regulatory factor 3, peroxisome proliferator-activated receptor-γ [PPARγ]) in macrophages to encourage inflammation resolution.78 Here, IL13 is linked to atherosclerosis.