C allele of CFH rs1329428 is a susceptible variant to AMD; on the other hand, it has been reported that T allele of CFH rs1329428 is known as a genetic susceptible variant to central serous chorioretinopathy (CSC)17–19 and with choroidal vascular hyperpermeability (CVH) and subfoveal choroidal thickness in eyes with PCV20. Here, CFH is linked to central serous retinopathy.