Importantly, Ebi3 expression could not be detected at d3, which corresponds to the IL-36–dependent KC36-dependent regulation of both IL-23 subunits (Fig 6 and Table 1), suggesting that it is IL-23 and not IL-39 which exerts functions at d3 of Aldara-induced psoriasis-like dermatitis. Here, IL23A is linked to psoriasis.