To characterize how the lack of IL-36 signaling in keratinocytes affects psoriasis-like dermatitis and the distribution of CD45+ subsets, FACS analysis was performed in Aldara-treated or untreated ears, draining and non-draining lymph nodes, spleen, and blood of WT, KO, FL, and DK mice at d3 and d7. This evidence concerns the gene PTPRC and psoriasis.