IL1RL2 and psoriasis 14, pustular: A causative mutation of IL-36Ra has been associated with generalized pustular psoriasis (GPP) (Marrakchi et al, 2011; Onoufriadis et al, 2011) and treatment with a monoclonal antibody targeting IL-36R showed clinical efficiency in seven GPP patients (Bachelez et al, 2019).