To further investigate the specific effects of NDRG2 on ovarian cancer cells, we conducted NDRG2 overexpression and NDRG2 silence in SKOV3, OVCAR-3, and CAOV3 cells by transfection with vector (negative control), NDRG2 OE, si-NC (negative control), or si-NDRG3. This evidence concerns the gene NDRG3 and ovarian cancer.