Of 782 patients with metastatic NSCLC who received EGFR-TKI in 1 L or 2 L+, 294 (37.6%) had subsequent therapy, while the remainder did not (235 [30.1%] died, 138 [17.6%] remained on initial EGFR-TKI, 51 [6.5%] discontinued EGFR-TKI, and 64 [8.2%] were lost to follow-up; Fig. 2). Here, EGFR is linked to non-small cell lung carcinoma.