For the remaining MYBPC3 HCM samples, variants were also found in the following other cardiomyopathy genes: ACTN2, LAMA4, LDB3, NEXN, PSEN2, TNNT2, and TTN. The remaining patient, HCM486, did not have an identifiable MYBPC3 variant, but an unreported mutation (c.T106C:p.C36R) was found in PLN. This evidence concerns the gene ACTN2 and cardiomyopathy.