In this regard, alterations in the expression of TRP Melastatin 2 (TRPM2), TRPM4, TRPM8, TRP Vanilloid 1 (TRPV1) and TRPV6 have been observed in PCa cells [38,39,40,41,42,43,44], some of them related to cancer cell survival. The gene discussed is TRPM8; the disease is cancer.