ACTB and colorectal cancer: Because phosphorylation of ZBP1 at Tyr396 by Src family kinases releases β-actin mRNA and elicits translation of β-actin [54], these findings suggest that the netrin receptor DCC (deleted in colorectal cancer) and the BDNF receptor TrkB activate Src family kinases to induce phosphorylation of ZBP1, thus initiating translation.