Using the AJCC TNM staging system for lung cancer [22], we observed that the CD44 rs713330 T/C polymorphism was highly associated with the “T” classification (AOR = 4.250, 95% CI = 1.529–11.814; p = 0.006) in male patients with lung adenocarcinoma (Table 4). Here, CD44 is linked to lung carcinoma.