Chemokine ligand (CCL) 20, a strong chemotactic for lymphocytes [59] that promotes growth of the prostate cancer cell line [60], and prolactin (PRL), which induces cell proliferation and differentiation via Src family tyrosine kinase [61] and the Jak2/Stat pathway [62], were upregulated during the down-regulation of BDH2. Here, JAK2 is linked to prostate cancer.