CD8A and neoplasm of oropharynx: Recently, Schneider et al. demonstrated a significantly higher infiltration of CD3+ and CD8+ T-lymphocytes in p16 positive oropharyngeal tumors, compared to p16 negative oropharyngeal, laryngeal, hypopharyngeal, and oral cavity carcinomas, but the CD8+ infiltrate did not correlate with patient’s prognosis [125].