IFNG and non-small cell lung carcinoma: For example, the autophagy-mediated MHC-I reduction seen in melanoma cells can be reversed through the addition of interferon-γ (IFN-γ) [96]; a finding supported in non-small-cell lung carcinoma (NSCLC), where radiotherapy-induced autophagy and IFN-γ secretion stimulated MHC-I expression in cancer cells and increased cytotoxic T-lymphocyte (CTL) infiltration [97].