Even though there has been a lack of evidence for a direct physical interaction between the MLV proteins and DYNLRB2 and a clear role on MLV traffic along microtubules, tools such as fluorescent label virions were p12 is tagged with GFP [22] will allow us to further confirm the essential role of dynein and its LC DYNLRB2 in MLV early infection. The gene discussed is DYNLRB2; the disease is infection.