Recent studies on biomarkers for the early detection of acute kidney injury (AKI) [8] have reported several biomarkers in experimental ischemic renal injury and clinical AKI, such as cystatin C [9], interleukin-18 [10], and neutrophil gelatinase-associated lipocalin [11], which result in a 50% increase in serum creatinine levels [12]. This evidence concerns the gene IL18 and acute kidney injury.