However, significant correlations were detected between the betatrophin levels and insulin levels (r=0.336, p=0.009), C-peptide levels (r=-0.399, p=0.002), and HOMA-IR scores (r=0.269, p=0.038) in the GDM group; they were not correlated with any other glucose or lipid parameter. The gene discussed is ANGPTL8; the disease is gestational diabetes.