To further confirm the relationship between surface receptor fucosylation (E-selectin binding potential) and intracellular signaling, AML blasts generated by MLL-AF9 transduction of HSCs from Fut4−/−Fut7−/− double gene-deleted mice or matching wild-type control mice, were adhered to precoated wells for 25 min. Here, FUT4 is linked to acute myeloid leukemia.