ZNF750 and metastatic malignant neoplasm in the lymph nodes: Strikingly, analysis of copy number alterations in 508 pairs of WGS revealed that ZNF750 copy number loss (n = 71) was statistically associated with more lymph node metastasis (P = 0.046) compared with patients harboring no deletions in ZNF750. Subsequently, Kaplan–Meier’s analysis revealed that patients with ZNF750 copy number loss developed more-frequent recurrence and had poorer survival (P = 0.048, Fig. 1g and Table S2).