As shown in Figure 1B–1E and Supplementary Table 2, NUDT1 mRNA expression positively correlates with the level of AFP expression (P = 0.000), pathological tumor stage (P = 0.038), tumor size (P=0.031), tumor grade (P = 0.000), and the degree of vascular invasion (P = 0.005). The gene discussed is AFP; the disease is neoplasm.