Hence, these additional findings further support the potential role of LAG3 in PD, and note the need for further investigation of the relationship between LAG3 and MHC II molecules, galectin-3 and liver sinusoidal endothelial cell lectin (LSECtin, another LAG3 identified ligand) [11], especially in PD pathogenesis. The gene discussed is CLEC4G; the disease is Parkinson disease.