The GO (Figure 3C) and KEGG (Supplementary Figure S4D) analysis results show that the blue module was more closely related to cell cycle, mitosis, nuclear division, p53 signaling pathway, etc., which possibly related to the excessive proliferation of cells during cancer, targeted by many classic anticancer drugs such as paclitaxel and navelbine [18,19,20], that play important roles in these processes. Here, TP53 is linked to cancer.