The phenotype score was derived from the phenotype match of the HPO profile used for Usher syndrome type II patients (Table S2) and OMIM:276901 (i.e., Usher syndrome, type 2A) as the most similar phenotypic annotation of USH2A found in OMIM via the PhenoDigm algorithm; Exomiser also reported the phenotype matches (with lower phenotype scores) found for a mouse mutant (0.496) and a zebrafish mutant (0.346) involving USH2A as well as a human disease, mouse mutant, and zebrafish mutant of the PDZD7 neighboring gene (0.538) found in the USH2A interactome via STRING analysis. This evidence concerns the gene PDZD7 and Usher syndrome type 2A.