PNPLA3 and steatosis: Similarly, in 200 adolescents, Nobili et al. demonstrated that the moderate intake of sweetened beverages led to increased hepatic fat deposition in PNPLA3 homozygous, and hampered consumption of vegetables declined the risk of severe steatosis, thus reporting a possible interaction between PNPLA3 I148M and dietary components regarding the severity of steatosis [62].