Finally, the rs4841132 G>A variant, enhancing the expression of Protein Phosphatase 1 Regulatory subunit 3B (PPP1R3B), which is involved in glycogen synthesis, has been recently reported to reduce the risk of NAFLD, but at the same time, may favor liver disease by facilitating glycogen accumulation [96,97]. The gene discussed is PPP1R3B; the disease is metabolic dysfunction-associated steatotic liver disease.