The effects of brefeldin A on protein transport blocks translocation of CRT/ERp57 complex in murine CT26 colon cancer cells treated with anticancer agents, such as oxaliplatin, anthracyclines, or UVC light, and, accordingly, the potential of CT26 cells to immunize mice against tumor development in vivo after anthracycline treatment was destroyed in the presence of brefeldin A [55]. Here, CALR is linked to malignant colon neoplasm.