ABCB1 and chronic myelogenous leukemia, BCR-ABL1 positive: One interesting phenomenon that we were able to identify in a model of chronic myeloid leukemia was the sequential activation of different ABC transporter expressions (ABCB1, ABCG2, ABCC1), as cells gained resistance to the tyrosine kinase inhibitor Imatinib [9], and the relatively unstable pattern of expression of these transporters in human samples [28].