In the Cardiovascular and Renal Microvascular Outcome Study with Linagliptin in Patients with Type 2 Diabetes Mellitus (CARMELINA study), the DPP4 inhibitor linagliptin retarded the albuminuria progression in patients with type 2 diabetes and high cardiovascular risk [11]. The gene discussed is DPP4; the disease is type 2 diabetes mellitus.