The comparison of secretome of autophagylow and autophagyhigh melanoma cells revealed that several proteins with established roles in inflammation and tumorigenesis, including interleukin-1β (IL-1β), chemokine C-X-C motif ligand 8 (CXCL8), leukemia inhibitory factor (LIF), family with sequence similarity 3 member C (FAM3), and dickkopf 3 (DKK3), were secreted at higher levels by melanoma cells with high activity of autophagy [81]. This evidence concerns the gene IL1B and melanoma.