GJA1 and myocardial ischemia: In this context, the aims of this work were to analyze changes in scar size and in left ventricular remodeling following transient myocardial ischemia followed by reperfusion in a Cx43Cre-ER(T)/fl mice model with partial (50%) or almost complete Cx43 deficiency after induction with 4-hydroxytamoxifen (4-OHT).