Consistent with this, real-time PCR for ICAM1 and VCAM1 gene expression in endothelial cells overlaid with control rHSVQ- or RAMBO-infected sarcoma cells showed a significant decrease in ICAM1 and VCAM1 induction in the endothelial cells co-cultured with RAMBO virus-infected sarcoma cells compared to rHSVQ-infected cells (Figure 3B). This evidence concerns the gene VCAM1 and sarcoma.