SOD1 and hereditary elliptocytosis: In this way, statistical analysis revealed significant SOD activity increase in HE patients with normal ammoniemia, as compared to controls (0.90 ± 0.08 vs. 1.35 ± 0.08, p < 0.0001), while in HE patients with high ammoniemia SOD activity was decreased, as compared to the control group (1.06 ± 0.07 vs. 1.35 ± 0.08 U/mL, p = 0.033) (Table 2).