One of these chemokines called MCP-1 (Monocyte chemoattractant protein-1) or CCL2 (C-C Motif Chemokine Ligand 2), has been described as the main chemoattractant mediator of monocytes/macrophages during renal inflammation, and is also related to fibrosis progression in different pathologies including DN [73,74]. This evidence concerns the gene CCL2 and liver dysplastic nodule.