EIF4E and breast cancer: A study has proposed β-catenin as a new eIF4E-targeted tumor promoting genelike MCL-1 and cyclin D. These authors showed that CGP57380 and cercosporamide prevent chemotherapy-induced eIF4E phosphorylation and β-catenin activation, inhibiting proliferation and inducing apoptosis of breast cancer cells in vitro and in vivo [65].