A number of inflammatory cytokines (IL‐1β, IL‐6, IL‐8, IL‐15, IL‐18, and IFN‐γ) have been shown to be elevated in mares with naturally occurring and experimentally induced placentitis.22, 23 In addition, several cytokines are involved in the pathophysiology of sepsis in neonatal foals.24 Here, IL18 is linked to Sepsis.