NANOS3 and testicular teratoma: In the case of crossing with Nanos3 mutant mice (Figs 5B and S4B), the ratio of affected male mice increased from 4.4% in wild-type male mice to 24.2% in Nanos3+/Cre male mice, indicating that Nanos3 is one of the genes responsible for testicular teratomas, as previously reported [25].