In 2017, we conducted a case–control study to explore the association between genetic variants in the interleukin (IL)-33/ST2 pathway and the risk of hypertension and found that a common polymorphism within the 3′ UTR of the ST2 gene interrupted the regulation of soluble (s)ST2 expression by miR-202-3p and promoted the occurrence of EH [18]. This evidence concerns the gene IL33 and hypertensive disorder.