TRPM6 and hypertensive disorder: Moreover, TRPM6, an identified target of miR-202-3p, encodes a transient receptor potential ion channel that plays an important role in the regulation of vascular tone and blood pressure [32,17], while MALAT-1, a long noncoding RNA targeted by miR-202-3p, was involved in vascular remodeling and promoted hypertension [33,34].