KMT2A and myelodysplastic syndrome: In our study, PLCB2 was negatively correlated with the prognosis of MDS Dnmt3b has been previously reported to suppress Myc‐induced lymphomagenesis in a mouse model, while loss of Dnmt3b accelerates MLL‐AF9 leukaemia progression via enhancing stemness and promoting cell cycle progression,26, 27, 28 which are consistent with our conclusion.