For example, liver hepatocellular carcinoma (LIHC) and kidney cancers (KIPAN), which originate from epithelial cells, showed the least Twist1 expression, whereas sarcoma (SARC) and uterine carcinosarcoma (UCS) that originate from mesenchymal cells showed higher expression, as previously shown at the level of EMT gene signatures (55). The gene discussed is TWIST1; the disease is sarcoma.