To further clarify the relationship between NF2 expression level and the prognosis of patients with breast cancer, the KM Plotter database analysis was used to show two survival curves of patients with high CD276 expression and low expression group (different probe), and ir was found that CD276 expression level has a significant impact on survival without distant metastasis and recurrence-free survival of patients (Figure 2.B, D). This evidence concerns the gene CD276 and breast cancer.