A more recent study, studying the NTSR1 expression in normal, benign prostatic hyperplasia (BPH), prostatic cancer and metastatic lymph nodes, there was no clear association between NTSR1 and age, PSA values, Gleason score, pathological T stage, but there was more frequent NTSR1 overexpression in metastatic lymph nodes compared to primary tumours (p = 0.038) [49]. This evidence concerns the gene NTSR1 and Familial prostate cancer.