In our study, under different concentrations of rapamycin, the cells overexpressing linc‐ROR showed higher viability than the negative control, and the overexpression of linc‐ROR could downregulate both the mRNA and protein expression levels of mTOR, indicating that linc‐ROR could promote breast cancer cell survival during rapamycin treatment by downregulating the expression of mTOR. This evidence concerns the gene MTOR and breast cancer.