Congenital Adrenal Hyperplasia (CAH) is an inherited autosomal recessive disorder with a 21-hydroxylase deficiency (21-OHD) due to mutations in the 21-hydroxylase (CYP21A2) gene accounting for 90 percent.1 Clinical manifestations depend on the degree of cortisol and aldosterone deficiency. Here, CYP21A2 is linked to classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency.