Furthermore, aberrant p53/KRASV12/c-Myc or p53/KRASV12/PI3K/AKT signaling is the minimum requirement for fallopian tube secretory epithelial cells (FTSECs) carcinogenesis [210], and increased copy number of PIK3CA has been observed in six fallopian tube carcinomas (FTCs) [211]. The gene discussed is PIK3CB; the disease is fallopian tube carcinoma.